Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.54 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.54 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.54 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.54 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.54 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.54 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.54 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.54 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4745288 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL79428 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL7995904 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL79427 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL29644896 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL29690600 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL4745286 | 0.84 | KDM4E (0.81) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| Hydrochloric Acid SCHEMBL27927566 | 0.82 | KDM4E (0.79) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| Hydrochloric Acid SCHEMBL6821836 | 0.82 | KDM4E (0.79) | KDM4ECYP1A2HSD17B10HDAC6MAPT | |
| SCHEMBL7651963 | 0.81 | PTGER3 (0.66) | CYP1A2HSD17B10MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498187-B1 | SUCH AS 2'-(6-CHLOROPIPERONYL)-3-(2,6-DICHLOROBENZYLOXY)-CINNAMIC ACID; ANTIBIOTICS | SMITHKLINE BEECHAM CORPORATION | 2002-12-24 | — | — | US | disclosed |