Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 12/20 | 0.48 |
| ▸ | F2 | P00734 | 11/20 | 0.48 |
| ▸ | F10 | P00742 | 11/20 | 0.48 |
| ▸ | F7 | P08709 | 11/20 | 0.48 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.48 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.48 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PLG | P00747 | 5/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665736 | 0.90 | F3 (0.51) | F3F2F10F7PRSS1 | |
| SCHEMBL7656288 | 0.86 | F3 (0.61) | F3F2F10F7PRSS1 | |
| SCHEMBL4627929 | 0.81 | ERN1 (0.47) | GAAKMT2AHPGDKDM4EERN1 | |
| SCHEMBL6348347 | 0.77 | F2 (0.55) | F3F2F10F7PRSS1 | |
| SCHEMBL7662054 | 0.77 | TSHR (0.61) | KMT2AHSD17B10KDM4EERN1MAPT | |
| SCHEMBL7664289 | 0.77 | F7 (0.55) | F3F2F10F7PRSS1 | |
| SCHEMBL7656638 | 0.76 | F3 (0.74) | F3F2F10F7PRSS1 | |
| SCHEMBL7663714 | 0.76 | F10 (0.54) | F3F2F10F7PRSS1 | |
| SCHEMBL7659886 | 0.75 | POLB (0.46) | F3F2F10F7PRSS1 | |
| SCHEMBL7688990 | 0.75 | F3 (0.63) | F3F2F10F7PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |