⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17675587 | 0.82 | — | — | |
| SCHEMBL16404862 | 0.82 | — | — | |
| SCHEMBL8515614 | 0.77 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL19210127 | 0.77 | — | — | |
| SCHEMBL8705311 | 0.76 | — | — | |
| SCHEMBL186805 | 0.76 | — | — | |
| SCHEMBL19128726 | 0.76 | — | — | |
| SCHEMBL3637989 | 0.76 | — | — | |
| SCHEMBL12850800 | 0.76 | — | — | |
| SCHEMBL260769 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12202826-B2 | N-pyridinyl acetamide derivatives as inhibitors of the Wnt signaling pathway | REDX PHARMA PLC (GB) | 2025-01-21 | — | — | US | disclosed |
| US-20230365549-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALING PATHWAY | REDX PHARMA PLC (GB) | 2023-11-16 | — | — | US | disclosed |
| US-11673907-B2 | Modular synthesis of aminoglycosides | REVAGENIX, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11643408-B2 | N-pyridinyl acetamide derivatives as inhibitors of the WNT signaling pathway | REDX PHARMA PLC (GB) | 2023-05-09 | — | — | US | disclosed |
| US-20230121489-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS WNT SIGNALLING PATHWAY INHIBITORS | REDX PHARMA PLC (GB) | 2023-04-20 | — | — | US | disclosed |
| EP-4071150-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS WNT SIGNALLING PATHWAY INHIBITORS | Redx Pharma Plc (GB) | 2022-10-12 | — | — | EP | disclosed |
| US-11459326-B2 | N-pyridinyl acetamide derivatives as Wnt signalling pathway inhibitors | REDX PHARMA PLC (GB) | 2022-10-04 | — | — | US | disclosed |
| EP-3204378-B3 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALLING PATHWAY | REDX PHARMA PLC (GB) | 2022-05-25 | — | — | EP | disclosed |
| US-20210046076-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS INHIBITORS OF THE WNT SIGNALING PATHWAY | REDX PHARMA PLC (GB) | 2021-02-18 | — | — | US | disclosed |
| US-20200407356-A1 | N-PYRIDINYL ACETAMIDE DERIVATIVES AS WNT SIGNALLING PATHWAY INHIBITORS | REDX PHARMA PLC (GB) | 2020-12-31 | — | — | US | disclosed |
| WO-2008075172-A2 | NICOTINAMIDE DERIVATIVES AS INHIBITORS OF H-PGDS AND THEIR USE FOR TREATING PROSTAGLANDIN D2 MEDIATED DISEASES | PFIZER PRODUCTS INC. (US) | 2008-06-26 | — | — | WO | disclosed |
| EP-1812542-A1 | FRAGRANCE COMBINATION COMPRISING 3,7-DIMETHYLOCT-6-ENE NITRILE (CITRONELLYL NITRILE) AS GERANONITRILE SUBSTITUTE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-08-01 | — | — | EP | disclosed |
| EP-1472232-B1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2007-01-24 | — | — | EP | disclosed |
| WO-2006053615-A1 | FRAGRANCE COMBINATION COMPRISING 3,7-DIMETHYLOCT-6-ENE NITRILE (CITRONELLYL NITRILE) AS GERANONITRILE SUBSTITUTE | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2006-05-26 | — | — | WO | disclosed |
| EP-1472232-A4 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORP (KR) | 2006-02-01 | — | — | EP | disclosed |
| EP-1472232-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | Yuhan Corporation (KR) | 2004-11-03 | — | — | EP | disclosed |
| US-6706888-B2 | REACTING A 3-HALOTETRAHYDROFURAN OR TETRAHYDROPYRAN COMPOUND WITH FORMAMIDINE OR ITS SALT IN THE PRESENCE OF A BASE TO PRODUCE A 3-(1H-IMIDAZOL-4-YL)PROPANOL DERIVATIVE; EFFICIENCY; INTERMEDIATES; ANTICARCINOGENIC AGENTS; VIRICIDES; | YUHAN CORPORATION (KR) | 2004-03-16 | — | — | US | disclosed |
| US-20030153769-A1 | Processes for preparing imidazole derivatives and salts thereof | YUHAN CORPORATION | 2003-08-14 | — | — | US | disclosed |
| WO-2003066600-A1 | PROCESSES FOR PREPARING IMIDAZOLE DERIVATIVES AND SALTS THEREOF | YUHAN CORPORATION (KR) | 2003-08-14 | — | — | WO | disclosed |
| US-4125542-A | INSECTICIDE | VELSICOL CHEMICAL CORPORATION (US) | 1978-11-14 | — | — | US | disclosed |