Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.46 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6671084 | 0.99 | KDM4E (0.61) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6674228 | 0.96 | KDM4E (0.61) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6673957 | 0.87 | KDM4E (0.56) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6674664 | 0.85 | KDM4E (0.56) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL7608308 | 0.84 | KDM4E (0.56) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6670959 | 0.80 | KDM4E (0.52) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6672034 | 0.80 | KDM4E (0.52) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6671710 | 0.77 | KDM4E (0.52) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| SCHEMBL6670970 | 0.77 | KDM4E (0.52) | KDM4EMEN1CYP1A2CYP2D6MAPT | |
| Aniracetam SCHEMBL70998 | 0.76 | KMT2A (1.00) | KDM4EMEN1CYP1A2CYP2D6MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355668-B1 | ANXIOLYTIC AGENTS; SIDE EFFECT REDUCTION | TAIHO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |