SCHEMBL7652725

SCHEMBL7652725

CS(=O)(=O)c1ccccc1COC(=O)N1CCN(Cc2cncn2Cc2ccc(C#N)cc2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 1.00
FNTB P49356 20/20 1.00
PGGT1B P53609 20/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7589808 0.88 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7594023 0.87 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL5583298 0.85 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7650931 0.83 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7681060 0.82 FNTA (0.74) FNTAFNTBPGGT1B
SCHEMBL7591131 0.82 FNTA (0.81) FNTAFNTBPGGT1B
SCHEMBL7652714 0.82 FNTA (0.83) FNTAFNTBPGGT1B
SCHEMBL7590316 0.81 FNTA (1.00) FNTAFNTBPGGT1B
SCHEMBL7154862 0.80 FNTA (0.73) FNTAFNTBPGGT1B
SCHEMBL7464811 0.77 FNTA (0.77) FNTAFNTBPGGT1B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358956-B1 IMIDAZOLYLALKYL-1-PIPERAZINE DERIVATIVES; FARNESYL-PROTEIN AND GERANYLGERANYL TRANSFERASE INHIBITORS; ANTICARCINOGENIC AGENTS MERCK & CO., INC. 2002-03-19 US disclosed