Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 16/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6508215 | 0.83 | ELANE (0.51) | ELANEHDAC6GLS | |
| SCHEMBL6504081 | 0.77 | ELANE (0.67) | ELANEHDAC6 | |
| SCHEMBL6505633 | 0.76 | ELANE (0.72) | ELANEHDAC6 | |
| SCHEMBL6810344 | 0.75 | ELANE (1.00) | ELANE | |
| SCHEMBL6498373 | 0.74 | ELANE (0.72) | ELANEHDAC6 | |
| SCHEMBL6505439 | 0.74 | ELANE (0.72) | ELANEHDAC6 | |
| SCHEMBL6507159 | 0.72 | ELANE (0.47) | ELANEHDAC6 | |
| SCHEMBL24095207 | 0.71 | HDAC6 (0.41) | ELANEHDAC6 | |
| SCHEMBL22525046 | 0.71 | ELANE (0.62) | ELANE | |
| SCHEMBL17432066 | 0.70 | KDM4E (0.63) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380189-B1 | FOR TREATING HERPES-RELATED DISORDERS | G.D. SEARLE & CO. | 2002-04-30 | — | — | US | disclosed |