Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 19/20 | 0.59 |
| ▸ | FNTB | P49356 | 19/20 | 0.59 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7661055 | 0.99 | FNTA (0.60) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| Lithium SCHEMBL7653538 | 0.99 | FNTA (0.59) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| Lithium Ion SCHEMBL7653530 | 0.92 | FNTA (0.58) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL7654971 | 0.92 | FNTA (0.68) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7657532 | 0.91 | FNTA (0.64) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7659414 | 0.90 | FNTA (0.63) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7658359 | 0.90 | FNTA (0.73) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL7655758 | 0.89 | FNTA (0.61) | FNTAFNTBCYP11B1CYP11B2 | |
| SCHEMBL7654962 | 0.88 | FNTA (0.59) | FNTAFNTBCYP11B1CYP11B2PGGT1B | |
| SCHEMBL7653602 | 0.88 | FNTA (0.67) | FNTAFNTBCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384061-B1 | HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS | LG CHEMICAL LTD. (KR) | 2002-05-07 | — | — | US | disclosed |