Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK1 | P06493 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7653952 | 1.00 | CDK1 (0.57) | CDK1GAAL3MBTL1CYP1A2TP53 | |
| SCHEMBL7658724 | 0.92 | CDK1 (0.68) | CDK1GAAL3MBTL1CYP1A2TP53 | |
| SCHEMBL7658737 | 0.92 | CDK1 (0.68) | CDK1GAAL3MBTL1CYP1A2TP53 | |
| SCHEMBL9080269 | 0.82 | CDK1 (0.62) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL11385667 | 0.81 | CDK1 (0.57) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL6945916 | 0.81 | CDK1 (0.53) | CDK1GAAL3MBTL1CYP1A2TP53 | |
| SCHEMBL6945901 | 0.81 | CDK1 (0.53) | CDK1GAAL3MBTL1CYP1A2TP53 | |
| SCHEMBL10395502 | 0.80 | CDK1 (0.56) | CDK1GAACYP1A2TP53GLA | |
| SCHEMBL8507050 | 0.80 | CDK1 (0.56) | CDK1GAAL3MBTL1CYP1A2TP53 | |
| SCHEMBL8536414 | 0.79 | CDK1 (0.80) | CDK1GAACYP1A2TP53GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410482-B1 | CONTROLLING WEEDS, GRASSES; COMPOUND CONTAINING PYRIMIDINE RING | HOECHST SCHERING AGREVO GMBH (DE) | 2002-06-25 | — | — | US | disclosed |