Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | NMUR2 | Q9GZQ4 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.36 |
| ▸ | FPR2 | P25090 | 3/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662615 | 0.95 | CA12 (0.38) | MAOBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL7663238 | 0.93 | EGFR (0.39) | MAOBNMUR2KDM4EMAPTMEN1 | |
| SCHEMBL7651944 | 0.89 | PPIA (0.39) | MAOAMAOBMAPTMEN1KMT2A | |
| SCHEMBL7852165 | 0.88 | SNCA (0.39) | MAOBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL926119 | 0.88 | KDM4E (0.40) | KDM4EMAPTMEN1KMT2ANPC1 | |
| SCHEMBL7655744 | 0.87 | NMUR2 (0.44) | MAOBNMUR2KDM4EMAPTMEN1 | |
| SCHEMBL7666892 | 0.87 | SNCA (0.45) | MAOBKDM4EMAPTMEN1KMT2A | |
| SCHEMBL7660127 | 0.86 | CCR3 (0.44) | MAPTMEN1KMT2A | |
| SCHEMBL7665046 | 0.86 | HIF1A (0.42) | MAPTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL7666776 | 0.85 | MAPT (0.38) | KDM4EMAPTMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6500846-B1 | 2-(4-CHLOROPHENYL)-7-METHOXYCHROMEN-4-ONE, AS CYCLIN-DEPENDENT KINASE INHIBITORS, USED AS ANTICARCINOGENIC AGENTS OR FOR PROPHYLAXIS OF NEURODEGENERATIVE DISEASE | LG CHEMICAL, LTD. (KR) | 2002-12-31 | — | — | US | disclosed |