Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LIPA | P38571 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.32 |
| ▸ | ADH1C | P00326 | 1/20 | 0.31 |
| ▸ | ADH1A | P07327 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29024443 | 0.93 | EPHX1 (0.37) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| SCHEMBL28399494 | 0.89 | LIPA (0.41) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| SCHEMBL7654055 | 0.84 | EPHX1 (0.41) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| Formic Acid SCHEMBL27989298 | 0.84 | EPHX1 (0.48) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| Formamide SCHEMBL27969822 | 0.79 | EPHX1 (0.44) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| Bicarbonate SCHEMBL28626633 | 0.78 | EPHX1 (0.48) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| Methyl Alcohol SCHEMBL27768087 | 0.78 | EPHX1 (0.50) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| SCHEMBL93482 | 0.78 | EPHX1 (0.48) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| SCHEMBL7739874 | 0.78 | EPHX1 (0.48) | EPHX1HTTSMN1; SMN2KDM4ELIPA | |
| SCHEMBL7741586 | 0.78 | EPHX1 (0.48) | EPHX1HTTSMN1; SMN2KDM4ELIPA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4618647-A | TWO POLYMERIZATION CATALYSTS | UNION CARBIDE CORP. (US) | 1986-10-21 | — | — | US | claimed |
| US-6491903-B1 | NARROW MOLECULAR WEIGHT DISTRIBUTION SHELL-CORE POLYMERS HAVING HYDROPHILIC, CROSSLINKED PERMEABLE SHELLS AND HYDROPHOBIC CORES, USED FOR REDUCING BLOOD CHOLESTEROL AND BILE ACID UPTAKE IN INTERSTINES; DRUG DELIVERY | WASHINGTON UNIVERSITY | 2002-12-10 | — | — | US | disclosed |
| US-6383500-B1 | Particles comprising amphiphilic copolymers, having a crosslinked shell domain and an interior core domain, useful for pharmaceutical and other applications | WASHINGTON UNIVERSITY | 2002-05-07 | — | — | US | disclosed |