Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGT2B17 | O75795 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4418524 | 0.77 | CA1 (0.41) | — | |
| SCHEMBL3668700 | 0.77 | CA1 (0.41) | — | |
| SCHEMBL9852673 | 0.75 | — | — | |
| SCHEMBL7662301 | 0.71 | — | — | |
| SCHEMBL4017056 | 0.70 | — | — | |
| SCHEMBL7911661 | 0.70 | CNR2 (0.33) | — | |
| SCHEMBL9593863 | 0.70 | KDM1A (0.36) | — | |
| SCHEMBL14394191 | 0.69 | — | — | |
| SCHEMBL3380327 | 0.68 | TRIM24 (0.35) | — | |
| SCHEMBL1784489 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384045-B1 | TREATMENT OF ALZHEIMER'S DISEASE AND ANTICANCER AGENTS | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION | 2002-05-07 | — | — | US | disclosed |
| US-5958970-A | ENZYME INHIBITORS OF ACETYLCHOLINESTERASE (ACHE) AND ACYL-COA:CHOLESTEROL ACYLTRANSFERASE (ACAT); USED IN THE TREATMENT OF ALZHEIMER'S DISEASE, ATHEROSCLEROSIS AND HYPERCHOLESTEROLEMIA | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1999-09-28 | — | — | US | disclosed |
| WO-1998039010-A1 | TRICYCLIC AND TETRACYCLIC PYRONES | KANSAS STATE UNIVERSITY RESEARCH FOUNDATION (US) | 1998-09-11 | — | — | WO | disclosed |