Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 18/20 | 0.54 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655582 | 1.00 | GRM5 (0.54) | GRM5PGRKCNH2 | |
| SCHEMBL7654264 | 1.00 | GRM5 (0.54) | GRM5PGRKCNH2 | |
| SCHEMBL10242113 | 1.00 | GRM5 (0.54) | GRM5PGRKCNH2 | |
| SCHEMBL10244102 | 0.86 | GRM5 (0.43) | GRM5PGRKCNH2 | |
| SCHEMBL10242287 | 0.83 | GRM5 (0.39) | GRM5PGRKCNH2 | |
| SCHEMBL13394570 | 0.81 | GRM5 (0.51) | GRM5PGRKCNH2 | |
| SCHEMBL13413571 | 0.81 | GRM5 (0.51) | GRM5PGRKCNH2 | |
| SCHEMBL10244382 | 0.81 | GRM5 (0.51) | GRM5PGRKCNH2 | |
| SCHEMBL10243637 | 0.81 | GRM5 (0.51) | GRM5PGRKCNH2 | |
| SCHEMBL1529217 | 0.81 | GRM5 (0.54) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6372911-B1 | REACTING COMPOUND CONTAINING AT LEAST ONE CARBON-CARBON DOUBLE BOND WITH CARBAMATE IN AQUEOUS SOLVENT IN PRESENCE OF BASE, OSMIUM CATALYST, CO-OXIDANT, AND OPTIONALLY ASYMMETRIC LIGAND, TO FORM REACTION MIXTURE CONTAINING BETA-HYDROXY CARBAMATE | MERCK & CO., INC. | 2002-04-16 | — | — | US | disclosed |