⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109524 | 0.74 | — | — | |
| SCHEMBL18324387 | 0.70 | — | — | |
| Urea SCHEMBL11244688 | 0.63 | — | — | |
| SCHEMBL2648603 | 0.60 | — | — | |
| SCHEMBL6974774 | 0.59 | — | — | |
| SCHEMBL4604333 | 0.59 | — | — | |
| SCHEMBL1020286 | 0.59 | — | — | |
| SCHEMBL8159740 | 0.56 | — | — | |
| SCHEMBL144134 | 0.56 | — | — | |
| SCHEMBL3835782 | 0.56 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-9152727-A | — | — | None | — | — | JP | disclosed |
| CN-106986807-B | 5- amino -4- nitro-pyrrole ketone compound and preparation method and application | 云南大学 | 2019-10-11 | — | — | CN | disclosed |
| CN-107522659-A | 3 nitroquinoline analog derivatives and its preparation method and application | 云南大学 | 2017-12-29 | — | — | CN | disclosed |
| CN-107089948-A | Fen derivative and its preparation method and application | 云南大学 | 2017-08-25 | — | — | CN | disclosed |
| CN-106986807-A | The nitro-pyrrole assimilation compound of 5 amino 4 and preparation method and application | 云南大学 | 2017-07-28 | — | — | CN | disclosed |
| US-20150342932-A1 | ANTI-VIRAL COMPOUNDS | KINETA INC (US) | 2015-12-03 | — | — | US | disclosed |
| US-9073946-B2 | Anti-viral compounds | Kineta, Inc. (US) | 2015-07-07 | — | — | US | disclosed |
| US-20090137500-A1 | Chemically synthesized doubled stranded micro-RNA (miRNA) molecule; nucleic acids with a pyrimidine modification | SIRNA THERAPEUTICS, INC. | 2009-05-28 | — | — | US | disclosed |
| WO-2008022281-A1 | SMALL MOLECULE INHIBITORS OF KYNURENINE-3-MONOOXYGENASE | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2008-02-21 | — | — | WO | disclosed |
| WO-2008022286-A2 | SMALL MOLECULE INHIBITORS OF KYNURENINE-3-MONOOXYGENASE | THE J. DAVID GLADSTONE INSTITUTES, A TESTAMENTARY TRUST ESTABLISHED UNDER THE WILL OF J. DAVID GLADSTONE (US) | 2008-02-21 | — | — | WO | disclosed |
| US-20020143117-A1 | POLYAMIDE COMPOSITIONS FOR WELDING | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-10-03 | — | — | US | disclosed |
| JP-H09152727-A | ALLYLENEDIAMINE DERIVATIVE AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE DERIVATIVE | MITA IND CO LTD | 1997-06-10 | — | — | JP | disclosed |