Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 4/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.43 |
| ▸ | FNTB | P49356 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655631 | 0.95 | PPARG (0.54) | PPARGPPARAFNTAFNTBALDH1A1 | |
| SCHEMBL7652717 | 0.91 | PPARG (0.61) | PPARGPPARAFNTAFNTBALDH1A1 | |
| SCHEMBL6003664 | 0.80 | PPARG (0.76) | PPARGPPARAPPARD | |
| SCHEMBL6003650 | 0.80 | PPARG (0.58) | PPARGPPARA | |
| Piperazine SCHEMBL6281879 | 0.78 | PPARG (0.70) | PPARGPPARAPPARD | |
| Tert-Butylamine SCHEMBL6277645 | 0.77 | PPARG (0.71) | PPARGPPARAPPARD | |
| SCHEMBL6275472 | 0.76 | PPARG (0.66) | PPARGPPARAPPARD | |
| Benzylamine SCHEMBL6280999 | 0.76 | PPARG (0.68) | PPARGPPARAPPARD | |
| SCHEMBL5434998 | 0.76 | PPARG (0.48) | PPARGPPARAFNTAFNTBALDH1A1 | |
| SCHEMBL6003721 | 0.75 | PPARG (0.62) | PPARGPPARAMAPTPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6440961-B1 | Tricyclic compounds and their use in medicine: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2002-08-27 | — | — | US | claimed |