Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 10/20 | 0.56 |
| ▸ | MEN1 | O00255 | 9/20 | 0.56 |
| ▸ | MAPT | P10636 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 4/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.56 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | NSD2 | O96028 | 1/20 | 0.51 |
| ▸ | BLM | P54132 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28018575 | 0.82 | DAGLA (0.64) | LMNANPC1RAB9ASMN1; SMN2DAGLA | |
| SCHEMBL13990397 | 0.75 | SMN1; SMN2 (0.46) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL2768791 | 0.75 | SMN1; SMN2 (0.46) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL2767621 | 0.75 | SMN1; SMN2 (0.46) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL1902177 | 0.75 | MAPT (0.62) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL1902176 | 0.75 | MAPT (0.62) | KMT2AMEN1MAPTLMNANPC1 | |
| SCHEMBL31285033 | 0.74 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL31285494 | 0.74 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL31284893 | 0.74 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTNPC1RAB9A | |
| SCHEMBL31284710 | 0.74 | SMN1; SMN2 (0.45) | KMT2AMEN1MAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6444694-B1 | ANTIPROLIFERATIVE AGENTS | WYETH | 2002-09-03 | — | — | US | disclosed |
| EP-0830345-B1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PROD (US) | 2001-09-05 | — | — | EP | disclosed |
| EP-0830345-A1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996039391-A1 | STYRYL BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-12 | — | — | WO | disclosed |