Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 7/20 | 0.40 |
| ▸ | CYP26A1 | O43174 | 4/20 | 0.40 |
| ▸ | ACHE | P22303 | 4/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7677763 | 1.00 | KDM4E (0.40) | KDM4EMEN1KMT2AMIFCYP26A1 | |
| SCHEMBL7655099 | 0.90 | MIF (0.41) | KDM4EMEN1KMT2AMIFCYP26A1 | |
| SCHEMBL7655105 | 0.90 | MIF (0.41) | KDM4EMEN1KMT2AMIFCYP26A1 | |
| SCHEMBL5582796 | 0.84 | MIF (0.45) | MIFCYP26A1ACHEBCHEMAOB | |
| SCHEMBL5582539 | 0.84 | MIF (0.45) | MIFCYP26A1ACHEBCHEMAOB | |
| SCHEMBL5582542 | 0.84 | MIF (0.45) | MIFCYP26A1ACHEBCHEMAOB | |
| SCHEMBL7677764 | 0.83 | MIF (0.33) | KDM4EMEN1KMT2AMIFCYP26A1 | |
| SCHEMBL7677769 | 0.82 | CYP26A1 (0.34) | KDM4EMEN1KMT2AMIFCYP26A1 | |
| SCHEMBL5582959 | 0.79 | MIF (0.48) | KDM4EMEN1KMT2AMIFCYP26A1 | |
| SCHEMBL5583024 | 0.79 | MIF (0.48) | KDM4EMEN1KMT2AMIFCYP26A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1218336-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | Takeda Chemical Industries, Ltd. (JP) | 2002-07-03 | — | — | EP | disclosed |
| WO-2001021577-A2 | MELANIN CONCENTRATING HORMONE ANTAGONIST | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-03-29 | — | — | WO | disclosed |