Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 17/20 | 0.68 |
| ▸ | F3 | P13726 | 16/20 | 0.68 |
| ▸ | F2 | P00734 | 16/20 | 0.68 |
| ▸ | F10 | P00742 | 16/20 | 0.68 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.68 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.68 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.68 |
| ▸ | PLG | P00747 | 8/20 | 0.55 |
| ▸ | PLAU | P00749 | 2/20 | 0.53 |
| ▸ | PLAT | P00750 | 1/20 | 0.53 |
| ▸ | F9 | P00740 | 1/20 | 0.52 |
| ▸ | F11 | P03951 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7654132 | 0.96 | F7 (0.64) | F7F3F2F10PRSS1 | |
| SCHEMBL7659983 | 0.88 | F2 (0.54) | F7F3F2F10PRSS1 | |
| SCHEMBL7659248 | 0.88 | F7 (0.68) | F7F3F2F10PRSS1 | |
| SCHEMBL7654139 | 0.87 | F10 (0.53) | F7F3F2F10PRSS1 | |
| SCHEMBL7657518 | 0.86 | F3 (0.80) | F7F3F2F10PRSS1 | |
| SCHEMBL7656487 | 0.85 | F7 (0.65) | F7F3F2F10PRSS1 | |
| SCHEMBL7658005 | 0.85 | F7 (0.75) | F7F3F2F10PRSS1 | |
| SCHEMBL7656387 | 0.85 | F7 (0.64) | F7F3F2F10PRSS1 | |
| SCHEMBL7661321 | 0.84 | F3 (0.74) | F7F3F2F10PRSS1 | |
| SCHEMBL7843743 | 0.84 | F7 (0.74) | F7F3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | claimed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | claimed |