Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 13/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 9/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 9/20 | 0.33 |
| ▸ | HTR3A | P46098 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650658 | 0.85 | F10 (0.39) | ALDH1A1CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL7652928 | 0.82 | CHRNA7 (0.32) | SMN1; SMN2CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL7653607 | 0.81 | CHRNA7 (0.33) | ALDH1A1SMN1; SMN2LMNAGAACHRNA7 | |
| SCHEMBL7063975 | 0.80 | CHRNA7 (0.40) | CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL6829677 | 0.78 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL7650292 | 0.78 | CHRNA7 (0.36) | CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL6805064 | 0.78 | CHRNA7 (0.43) | CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL7062994 | 0.77 | CHRNA7 (0.38) | CHRNA7CHRNB2CHRNA4HTR3A | |
| SCHEMBL7123087 | 0.77 | CHRNA7 (0.36) | CHRNA7CHRNB2CHRNA4 | |
| SCHEMBL6008261 | 0.77 | CHRNA7 (0.41) | CHRNA7CHRNB2CHRNA4HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492385-B2 | CENTRAL NERVOUS SYSTEM DISORDERS | PHARMACIA & UPJOHN COMPANY | 2002-12-10 | — | — | US | claimed |