Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ACACB | O00763 | 12/20 | 0.43 |
| ▸ | NAAA | Q02083 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13720815 | 0.85 | ACACB (0.49) | KMT2AMEN1ACACBNAAAFFAR1 | |
| SCHEMBL20306371 | 0.82 | ACACB (0.51) | KMT2AMEN1ACACBFFAR1NPSR1 | |
| SCHEMBL12160713 | 0.82 | ACACB (0.51) | KMT2AMEN1ACACBFFAR1NPSR1 | |
| SCHEMBL29152373 | 0.80 | NPSR1 (0.51) | KMT2AMEN1ACACBFFAR1NPSR1 | |
| SCHEMBL5520546 | 0.80 | SLC6A4 (0.51) | KMT2AMEN1 | |
| SCHEMBL18234087 | 0.80 | HTR2A (0.42) | KMT2AMEN1NAAA | |
| SCHEMBL13439687 | 0.80 | NPSR1 (0.51) | KMT2AMEN1ACACBFFAR1NPSR1 | |
| SCHEMBL7660770 | 0.80 | SMN1; SMN2 (0.51) | DDB1CRBN | |
| SCHEMBL13439689 | 0.79 | ACACB (0.44) | KMT2AMEN1ACACBNAAAFFAR1 | |
| SCHEMBL2016296 | 0.78 | EPHX2 (0.43) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384065-B1 | CONTROL THE FUNCTIONS OF PROTEINS SUCH AS ENZYMES AND RECEPTOR FORTREATING INFLAMMATORY DISEASES SUCH AS RHEUMATOID ARTHRITIS, | TOYAMA CHEMICAL CO., LTD. (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-1076056-A1 | NOVEL SPIRO COMPOUNDS OR SALTS THEREOF AND PREVENTIVES/REMEDIES FOR AUTOIMMUNE DISEASES AND AP-1 INHIBITORS CONTAINING THE SAME | TOYAMA CHEMICAL CO., LTD. (JP) | 2001-02-14 | — | — | EP | disclosed |