Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 14/20 | 0.52 |
| ▸ | NQO2 | P16083 | 2/20 | 0.52 |
| ▸ | F10 | P00742 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.52 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.52 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.52 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.52 |
| ▸ | PLG | P00747 | 1/20 | 0.52 |
| ▸ | PLAT | P00750 | 1/20 | 0.52 |
| ▸ | PROC | P04070 | 1/20 | 0.52 |
| ▸ | HPN | P05981 | 1/20 | 0.52 |
| ▸ | SLC47A2 | Q86VL8 | 1/20 | 0.52 |
| ▸ | SLC47A1 | Q96FL8 | 1/20 | 0.52 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7672765 | 0.88 | F2 (0.58) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL7654564 | 0.87 | NQO2 (0.65) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL6785394 | 0.80 | F2 (0.62) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL6778939 | 0.77 | NQO2 (0.72) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL28140926 | 0.77 | NQO2 (0.64) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL6778873 | 0.77 | NQO2 (0.69) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL6776070 | 0.76 | NQO2 (0.84) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL6784887 | 0.76 | NQO2 (0.79) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL5826270 | 0.76 | F2 (0.62) | F2NQO2F10PRSS1PRSS2 | |
| SCHEMBL28141604 | 0.75 | NQO2 (0.71) | F2NQO2F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6414008-B1 | CYNAO- OR AMIDINE-SUBSTITUTED BENZIMIDAZOLES, BENOTHIAZOLES, OR BENZOXAZOLES; 2-(N-(4-AMIDINOPHENYL)AMINOMETHYL)BENZOTHIAZOLES; 2-((4-CYANOPHENYL)OXYMETHYL)IMIDAZOL(4,5-B)PYRIDINES; ANTITHROMBOTICS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-07-02 | — | — | US | disclosed |