⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19952902 | 0.73 | — | — | |
| SCHEMBL2497301 | 0.69 | — | — | |
| SCHEMBL4776631 | 0.59 | — | — | |
| SCHEMBL12601793 | 0.59 | — | — | |
| SCHEMBL4786313 | 0.59 | — | — | |
| SCHEMBL8988872 | 0.59 | — | — | |
| SCHEMBL12154070 | 0.59 | — | — | |
| SCHEMBL13651618 | 0.54 | — | — | |
| SCHEMBL7849746 | 0.54 | — | — | |
| SCHEMBL19386537 | 0.53 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6413986-B1 | ALZHEIMER'S DISEASE | AVENTIS PHARMACEUTICALS INC. | 2002-07-02 | — | — | US | disclosed |
| EP-0535496-A1 | (1-Indanon-2yl)methylpiperidines, intermediates and a process for their preparation and their use as medicaments | HOECHST-ROUSSEL PHARMACEUTICALS INCORPORATED (US) | 1993-04-07 | — | — | EP | disclosed |