Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 13/20 | 0.74 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.47 |
| ▸ | PDE5A | O76074 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PDE1A | P54750 | 1/20 | 0.47 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.47 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656475 | 1.00 | CACNA1B (0.74) | CACNA1BPDE1CPDE2APDE5ACYP2C9 | |
| SCHEMBL7656478 | 1.00 | CACNA1B (0.74) | CACNA1BPDE1CPDE2APDE5ACYP2C9 | |
| SCHEMBL7527521 | 0.87 | CACNA1B (0.72) | CACNA1BPDE4D | |
| SCHEMBL7527518 | 0.87 | CACNA1B (0.72) | CACNA1BPDE4D | |
| SCHEMBL7659984 | 0.86 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL7659989 | 0.86 | CACNA1B (1.00) | CACNA1B | |
| SCHEMBL7662973 | 0.85 | CACNA1B (0.81) | CACNA1BPDE4D | |
| SCHEMBL7660929 | 0.82 | CACNA1B (0.73) | CACNA1BPDE4D | |
| SCHEMBL7660932 | 0.82 | CACNA1B (0.73) | CACNA1BPDE4D | |
| SCHEMBL7662276 | 0.79 | CACNA1B (0.85) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350762-B1 | SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1043314-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-10-11 | — | — | EP | disclosed |