SCHEMBL7656597

SCHEMBL7656597

Cc1c(C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F)cc2ccccc2c1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.47
KDM4E B2RXH2 3/20 0.47
HPGD P15428 3/20 0.47
MEN1 O00255 2/20 0.47
ALDH1A1 P00352 2/20 0.47
CYP1A2 P05177 1/20 0.47
GLA P06280 1/20 0.47
CYP2C19 P33261 1/20 0.47
HSD17B10 Q99714 1/20 0.47
PDE10A Q9Y233 3/20 0.41
TSHR P16473 1/20 0.39
DHODH Q02127 10/20 0.39
L3MBTL1 Q9Y468 2/20 0.35
ME2 P23368 1/20 0.34
ME1 P48163 1/20 0.34
ME3 Q16798 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC7 Q8WUI4 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
HDAC6 Q9UBN7 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7653270 0.81 KDM4E (0.45) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL7655987 0.81 KDM4E (0.45) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL7650892 0.79 KDM4E (0.46) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL7653548 0.75 KDM4E (0.47) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL11785232 0.72 MEN1 (0.61) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL497405 0.72 KMT2A (0.66) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL16232413 0.70 KMT2A (0.63) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL4790076 0.70 KMT2A (0.58) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL3370837 0.70 MEN1 (0.58) KMT2AKDM4EHPGDMEN1ALDH1A1
SCHEMBL27616553 0.69 KMT2A (0.61) KMT2AKDM4EHPGDMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6383274-B1 Ink jet ink compositions and printing processes XEROX CORPORATION 2002-05-07 US claimed
US-6383274-B1 Ink jet ink compositions and printing processes XEROX CORPORATION 2002-05-07 US disclosed