Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 16/20 | 0.47 |
| ▸ | F2 | P00734 | 15/20 | 0.47 |
| ▸ | F10 | P00742 | 14/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.47 |
| ▸ | F9 | P00740 | 2/20 | 0.47 |
| ▸ | PLAU | P00749 | 2/20 | 0.47 |
| ▸ | F11 | P03951 | 2/20 | 0.47 |
| ▸ | F3 | P13726 | 13/20 | 0.47 |
| ▸ | PLG | P00747 | 5/20 | 0.45 |
| ▸ | GPR132 | Q9UNW8 | 2/20 | 0.42 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7656616 | 1.00 | F7 (0.47) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7651999 | 0.91 | F7 (0.51) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7659236 | 0.90 | F7 (0.50) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7659229 | 0.90 | F7 (0.50) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7660781 | 0.88 | F7 (0.55) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7660792 | 0.88 | F7 (0.55) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7653754 | 0.88 | F7 (0.63) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7660872 | 0.86 | F10 (0.47) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7660863 | 0.85 | F7 (0.52) | F7F2F10PRSS1PRSS2 | |
| SCHEMBL7660150 | 0.85 | F3 (0.58) | F7F2F10PRSS1PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |