Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 16/20 | 0.56 |
| ▸ | F3 | P13726 | 16/20 | 0.56 |
| ▸ | F2 | P00734 | 15/20 | 0.56 |
| ▸ | F10 | P00742 | 15/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | PLG | P00747 | 7/20 | 0.53 |
| ▸ | F9 | P00740 | 2/20 | 0.49 |
| ▸ | PLAU | P00749 | 2/20 | 0.49 |
| ▸ | F11 | P03951 | 2/20 | 0.49 |
| ▸ | KLK1 | P06870 | 2/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7682011 | 0.96 | F3 (0.60) | F7F3F2F10PRSS1 | |
| SCHEMBL7656670 | 0.91 | F10 (0.49) | F7F3F2F10PRSS1 | |
| SCHEMBL7662237 | 0.87 | F3 (0.61) | F7F3F2F10PRSS1 | |
| SCHEMBL7651435 | 0.87 | F10 (0.51) | F7F3F2F10PRSS1 | |
| SCHEMBL7659148 | 0.85 | F3 (0.59) | F7F3F2F10PRSS1 | |
| SCHEMBL7655002 | 0.84 | F3 (0.66) | F7F3F2F10PRSS1 | |
| Trifluoroacetic Acid SCHEMBL7661623 | 0.83 | F7 (0.63) | F7F3F2F10PRSS1 | |
| SCHEMBL7659231 | 0.82 | F3 (0.64) | F7F3F2F10PRSS1 | |
| SCHEMBL7656252 | 0.82 | F3 (0.54) | F7F3F2F10PRSS1 | |
| SCHEMBL7660120 | 0.79 | F7 (0.60) | F7F3F2F10PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |