Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.48 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | DRD3 | P35462 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.47 |
| ▸ | SLC1A1 | P43005 | 3/20 | 0.47 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.47 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.47 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957876 | 1.00 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL28444248 | 1.00 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL15609874 | 1.00 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL15609557 | 1.00 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| SCHEMBL417500 | 1.00 | CHRM1 (0.48) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL28446672 | 0.98 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL15609267 | 0.98 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL6379154 | 0.98 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL15539631 | 0.98 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C | |
| Hydrochloric Acid SCHEMBL3692631 | 0.98 | CHRM1 (0.46) | CHRM1AKR1A1CHRM3HTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 127 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200140844-A1 | CRISPR NANOCOMPLEX FOR NONVIRAL GENOME EDITING AND METHOD FOR PREPARING THE SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-05-07 | — | — | US | claimed |
| CN-104926920-B | Protein and peptide drugs N-terminal pinpoints polyethyleneglycol modified method | 浙江医药高等专科学校 | 2019-08-09 | — | — | CN | claimed |
| CN-104927044-B | The preparation method of high-purity polyethylene glycol aldehyde derivative | 浙江医药高等专科学校 | 2018-02-23 | — | — | CN | claimed |
| CN-104861161-B | A kind of method for preparing Amino End Group polyethylene glycol | 浙江医药高等专科学校 | 2017-05-31 | — | — | CN | claimed |
| CN-104927044-A | Preparation method of high-purity polyethylene glycol aldehyde derivative | ZHEJIANG PHARMACEUTICAL COLLEGE | 2015-09-23 | — | — | CN | claimed |
| CN-104926920-A | Protein polypeptide drug N-terminal fixed-point polyethylene glycol modification method | ZHEJIANG PHARMACEUTICAL COLLEGE | 2015-09-23 | — | — | CN | claimed |
| CN-104861161-A | Method for preparing amino-terminated polyethylene glycol | ZHEJIANG PHARMACEUTICAL COLLEGE | 2015-08-26 | — | — | CN | claimed |
| CN-104812733-A | A method for the preparation of 3-amino-n-cyclopropyl-2-hydroxyl-hexanamide | JANSSEN PHARMACEUTICA NV | 2015-07-29 | — | — | CN | claimed |
| EP-2861557-A1 | A METHOD FOR THE PREPARATION OF 3-AMINO-N-CYCLOPROPYL-2-HYDROXYL-HEXANAMIDE | Janssen Pharmaceutica, N.V. (BE) | 2015-04-22 | — | — | EP | claimed |
| WO-2013186248-A1 | A METHOD FOR THE PREPARATION OF 3-AMINO-N-CYCLOPROPYL-2-HYDROXYL-HEXANAMIDE | JANSSEN PHARMACEUTICA NV (BE) | 2013-12-19 | — | — | WO | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-11319533-B2 | CRISPR nanocomplex for nonviral genome editing and method for preparing the same | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2022-05-03 | — | — | US | disclosed |
| CN-108017552-B | Synthetic method of alpha-hydroxy-beta-amino acid single stereoisomer | 康化（上海）新药研发有限公司 | 2020-08-14 | — | — | CN | disclosed |
| US-20200140844-A1 | CRISPR NANOCOMPLEX FOR NONVIRAL GENOME EDITING AND METHOD FOR PREPARING THE SAME | KOREA ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2020-05-07 | — | — | US | disclosed |
| CN-104926920-B | Protein and peptide drugs N-terminal pinpoints polyethyleneglycol modified method | 浙江医药高等专科学校 | 2019-08-09 | — | — | CN | disclosed |
| WO-2002008256-A2 | PEPTIDES AS NS3-SERINE PROTEASE INHIBITORS OF HEPATITIS C VIRUS | SCHERING CORPORATION (US) | 2002-01-31 | — | — | WO | disclosed |
| WO-2001097781-A1 | POSITIVELY CHARGED POLY[ALPHA-(OMEGA-AMINOALKYL) GLYCOLIC ACID] FOR THE DELIVERY OF A BIOACTIVE AGENT VIA TISSUE AND CELLULAR UPTAKE | EXPRESSION GENETICS, INC. (US) | 2001-12-27 | — | — | WO | disclosed |
| EP-1140854-A2 | METHODS FOR THE SYNTHESIS OF ALPHA-HYDROXY-BETA-AMINO ACID AND AMIDE DERIVATIVES | CORVAS INTERNATIONAL, INC. (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035868-A2 | METHODS FOR THE SYNTHESIS OF ALPHA-HYDROXY-BETA-AMINO ACID AND AMIDE DERIVATIVES | CORVAS INTERNATIONAL, INC. (US) | 2000-06-22 | — | — | WO | disclosed |
| US-5541290-A | OLIGOPEPTIDE CONTAINING ALPHA-KETOAMIDE GROUP, TREATMENT OF ALZHEIMER*S DISEASE AND OTHER NEURODEGENERATIVE DISORDERS | CORTEX PHARMACEUTICALS, INC. | 1996-07-30 | — | — | US | disclosed |