Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1B | Q00975 | 12/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | PDE1C | Q14123 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7665052 | 0.98 | CACNA1B (0.53) | CACNA1BADRA1APDE1CMEN1MAPT | |
| SCHEMBL7667045 | 0.95 | CACNA1B (0.54) | CACNA1BADRA1AMEN1MAPTKMT2A | |
| SCHEMBL5855231 | 0.92 | CACNA1B (0.58) | CACNA1B | |
| SCHEMBL7663854 | 0.91 | CACNA1B (0.47) | CACNA1BADRA1A | |
| SCHEMBL27541930 | 0.91 | CACNA1B (0.58) | CACNA1BPDE1C | |
| SCHEMBL7663100 | 0.88 | CACNA1B (0.54) | CACNA1BADRA1A | |
| SCHEMBL4507052 | 0.87 | CACNA1B (0.64) | CACNA1BPDE1C | |
| SCHEMBL4496949 | 0.87 | CACNA1B (0.67) | CACNA1BADRA1A | |
| SCHEMBL27541957 | 0.85 | CACNA1B (0.55) | CACNA1B | |
| SCHEMBL5855031 | 0.85 | CACNA1B (0.63) | CACNA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350762-B1 | SELECTIVELY INHIBIT THE ACTION OF N-TYPE CALCIUM CHANNEL; | AJINOMOTO CO., INC. (JP) | 2002-02-26 | — | — | US | disclosed |
| EP-1043314-A1 | NOVEL DIHYDROPYRIDINE DERIVATIVE | Ajinomoto Co., Inc. (JP) | 2000-10-11 | — | — | EP | disclosed |