SCHEMBL7656859

SCHEMBL7656859

COC(=O)Cc1cccc(CCC(CO)n2cnc(C(N)=O)c2)c1

nearest known ligand 0.68

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ADA P00813 19/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7669799 0.87 ADA (0.52) ADA
SCHEMBL7457279 0.86 ADA (0.78) ADA
SCHEMBL7670504 0.84 ADA (0.75) ADA
SCHEMBL7656871 0.84 ADA (0.46) ADA
SCHEMBL7664981 0.83 ADA (0.77) ADA
SCHEMBL7668671 0.83 ADA (0.77) ADA
Fr-221647 SCHEMBL7659103 0.81 ADA (1.00) ADA
SCHEMBL7452591 0.80 ADA (0.66) ADA
SCHEMBL7669806 0.80 ADA (0.43) ADA
SCHEMBL7659436 0.80 ADA (0.71) ADA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6359145-B1 ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2002-03-19 US disclosed