SCHEMBL765716

SCHEMBL765716

CC(N)CF

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13088904 1.00
SCHEMBL5369505 1.00
Hydrochloric Acid SCHEMBL3934119 0.96
Hydrochloric Acid SCHEMBL755298 0.96
Hydrochloric Acid SCHEMBL3931726 0.96
SCHEMBL21921142 0.75
SCHEMBL586900 0.75
SCHEMBL11056284 0.73
SCHEMBL23776843 0.72
SCHEMBL10002484 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 148 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103958502-A Quinazoline compounds as serine/threonine kinase inhibitors ARRAY BIOPHARMA INC 2014-07-30 CN claimed
CN-101193884-A Tubulin inhibitor and process for its preparation WYETH CORP (US) 2008-06-04 CN claimed
US-20010003744-A1 Therapeutic compounds CHAMBERLAIN STANLEY DAWES (US) 2001-06-14 US claimed
US-6077832-A FOR THERAPY AND PROPHYLAXIS OF HERPES VIRUS INFECTION GLAXO WELLCOME INC. (US) 2000-06-20 US claimed
EP-0769017-B1 THERAPEUTIC COMPOUNDS WELLCOME FOUND (GB) 2000-05-24 EP claimed
CN-1052010-C Benzimidazole derivatives, method for the production thereof, use thereof and pharmaceutical preparations containing the same WELLCOME FOUND (GB) 2000-05-03 CN claimed
CN-1159194-A Therapeutic compounds WELLCOME FOUND (GB) 1997-09-10 CN claimed
WO-1996001833-A1 THERAPEUTIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1996-01-25 WO claimed
EP-4371987-B9 SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS AS HPK1 INHIBITORS GILEAD SCIENCES INC (US) 2025-11-26 EP disclosed
EP-4371987-B1 SUBSTITUTED 6-AZABENZIMIDAZOLE COMPOUNDS AS HPK1 INHIBITORS GILEAD SCIENCES INC (US) 2025-09-17 EP disclosed
US-20250270190-A1 KIT INHIBITORS BLUEPRINT MEDICINES CORPORATION 2025-08-28 US disclosed
EP-4578451-A2 COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS Novartis AG (CH) 2025-07-02 EP disclosed
EP-4214210-B1 COMPOUNDS AND COMPOSITIONS AS SPPL2A INHIBITORS NOVARTIS AG (CH) 2025-04-09 EP disclosed
US-12258346-B2 Substituted 6-azabenzimidazole compounds GILEAD SCIENCES, INC. (US) 2025-03-25 US disclosed
CN-1052010-C Benzimidazole derivatives, method for the production thereof, use thereof and pharmaceutical preparations containing the same WELLCOME FOUND (GB) 2000-05-03 CN disclosed
US-5998605-A Antiviral benzimidazole nucleoside analogues and method for their preparation GLAXO WELLCOME INC. (US) 1999-12-07 US disclosed
CN-1236616-A Application of benzimidazole derivatives in preparing medicine WELLCOME FOUND (GB) 1999-12-01 CN disclosed
WO-1999033790-A1 INSECTICIDAL FLUORO-SUBSTITUTED BENZOYLUREAS NIHON BAYER AGROCHEM K.K. (DE) 1999-07-08 WO disclosed
CN-1159194-A Therapeutic compounds WELLCOME FOUND (GB) 1997-09-10 CN disclosed
WO-1996001833-A1 THERAPEUTIC COMPOUNDS THE WELLCOME FOUNDATION LIMITED (GB) 1996-01-25 WO disclosed