Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 3/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657276 | 1.00 | LY96 (0.58) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7108281 | 0.92 | LY96 (0.65) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7108279 | 0.92 | LY96 (0.65) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7110370 | 0.90 | LY96 (0.56) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7110372 | 0.90 | LY96 (0.56) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7115605 | 0.88 | LY96 (0.58) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7115603 | 0.88 | LY96 (0.58) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7107471 | 0.86 | LY96 (0.52) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7107467 | 0.86 | LY96 (0.52) | LY96LMNAHPGDHTTMAPT | |
| SCHEMBL7109500 | 0.86 | LY96 (0.58) | LY96LMNAHPGDHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350778-B1 | CARDIOVASCULAR DISORDERS | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2002-02-26 | — | — | US | disclosed |