SCHEMBL7657320

SCHEMBL7657320

CCc1ccc2c(ccc3cc(F)ccc32)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.50
CYP2A6 P11509 2/20 0.50
LMNA P02545 2/20 0.42
SLC6A2 P23975 3/20 0.38
SLC6A4 P31645 3/20 0.38
KCNH2 Q12809 3/20 0.38
SLC6A3 Q01959 2/20 0.38
CYP19A1 P11511 1/20 0.38
KIF11 P52732 1/20 0.38
AKR1C3 P42330 1/20 0.38
AKR1C2 P52895 1/20 0.38
TRPA1 O75762 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
DAO P14920 2/20 0.36
ELANE P08246 1/20 0.36
GAA P10253 2/20 0.36
NPC1 O15118 1/20 0.34
ALDH1A1 P00352 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12017103 0.90 CYP1A2 (0.61) CYP1A2CYP2A6LMNASLC6A2SLC6A4
SCHEMBL14604942 0.88 CYP1A2 (0.59) CYP1A2CYP2A6LMNASLC6A2SLC6A4
SCHEMBL7661607 0.85 SLC6A2 (0.43) CYP1A2CYP2A6LMNASLC6A2SLC6A4
SCHEMBL7661369 0.82 SKP2 (0.42) SLC6A2SLC6A4KCNH2SLC6A3KMT2A
SCHEMBL7666172 0.80 DHODH (0.43) LMNASLC6A2SLC6A4KCNH2SLC6A3
SCHEMBL14604946 0.80 CYP19A1 (0.50) CYP1A2CYP2A6LMNACYP19A1KIF11
SCHEMBL7658422 0.79 DHODH (0.44) LMNASLC6A2SLC6A4SLC6A3ALDH1A1
SCHEMBL26036280 0.78 CYP1A2 (0.44) CYP1A2CYP2A6LMNAKIF11AKR1C3
SCHEMBL3172468 0.78 CYP1A2 (0.41) CYP1A2CYP2A6LMNAKIF11AKR1C3
SCHEMBL3161621 0.78 CYP1A2 (0.41) CYP1A2CYP2A6LMNAL3MBTL1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6495220-B2 WITH POSITIVE DIELECTRIC ANISOTROPY AND FAVORABLE VISCOSITY; THERMAL, LIGHT AND ULTRAVIOLET STABILITY; USE IN PORTABLE TELEPHONES AND NOTEBOOK COMPUTERS CLARIANT INTERNATIONAL LTD. (CH) 2002-12-17 US disclosed
US-20010023935-A1 With positive dielectric anisotropy and favorable viscosity; thermal, light and ultraviolet stability; use in portable telephones and notebook computers CLARIANT INTERNATIONAL LTD. (CH) 2001-09-27 US disclosed