Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 11/20 | 0.48 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.48 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.48 |
| ▸ | GMNN | O75496 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998913 | 0.86 | ADORA1 (0.52) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL7666412 | 0.80 | ADORA1 (0.51) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL7662109 | 0.78 | ADORA1 (0.48) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL7000539 | 0.78 | ADORA1 (0.54) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL7668320 | 0.77 | ADORA1 (0.53) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL8567698 | 0.71 | ADORA1 (0.48) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL8559082 | 0.65 | ADORA1 (0.62) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL7669969 | 0.65 | ADORA1 (0.40) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL8561107 | 0.65 | ADORA1 (0.63) | ADORA3ADORA1ADORA2AADORA2BGMNN | |
| SCHEMBL7001362 | 0.64 | KMT2A (0.48) | ADORA3ADORA1ADORA2AADORA2BLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492377-B1 | Imidazotriazolopyrimidines with adenosine-antagonistic activity | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |