SCHEMBL7657536

SCHEMBL7657536

Cc1ccc(-c2nc(Oc3cccc(C(=O)N(C)C)c3)cc(Oc3cc(C(=N)N)ccc3O)n2)cc1

nearest known ligand 0.75

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
F10 P00742 17/20 0.75
F2 P00734 13/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6576569 0.88 F10 (0.92) F10F2
SCHEMBL6579580 0.87 F10 (0.87) F10F2
SCHEMBL6579120 0.86 F10 (1.00) F10F2
SCHEMBL6578487 0.86 F10 (0.89) F10F2
SCHEMBL6580631 0.81 F10 (0.80) F10F2
SCHEMBL7054526 0.79 F10 (0.73) F10F2
SCHEMBL6578534 0.79 F10 (1.00) F10F2
SCHEMBL6579223 0.79 F10 (0.75) F10F2
SCHEMBL7372165 0.79 F10 (0.77) F10F2
SCHEMBL6576443 0.79 F10 (0.82) F10F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6372751-B1 DRUGS WITH BENZENE AND PYRIMIDINE RINGS BERLEX LABORATORIES, INC. 2002-04-16 US disclosed
US-6127376-A A BLOOD FACTOR XA ENZYME INHIBITOR TREATING A HUMAN HAVING A DISEASE-STATE CHARACTERIZED BY THROMBOTIC ACTIVITY BERLEX LABORATORIES, INC. (US) 2000-10-03 US disclosed