Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.35 |
| ▸ | HPGD | P15428 | 7/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | RAB9A | P51151 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | PARP1 | P09874 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763045 | 0.77 | KDM4E (0.41) | MAPTSMN1; SMN2TP53ALDH1A1HPGD | |
| SCHEMBL7467683 | 0.73 | PIM1 (0.43) | PIM1MAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL14461193 | 0.73 | PIM1 (0.50) | PIM1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL73268 | 0.73 | PIM1 (0.49) | PIM1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL5492669 | 0.72 | BCHE (0.40) | ALDH1A1KDM4EHSD17B10PARP1GAA | |
| SCHEMBL7330146 | 0.71 | PIM1 (0.48) | PIM1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL28724197 | 0.68 | PIM1 (0.43) | PIM1MAPTSMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6466501 | 0.68 | MAPT (0.69) | PIM1MAPTSMN1; SMN2TP53ALDH1A1 | |
| SCHEMBL4723685 | 0.68 | ABCG2 (0.43) | MAPTSMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL14461166 | 0.67 | PIM1 (0.45) | PIM1MAPTALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6395897-B1 | DRUGS FOR ENZYME INHIBITORS ANTICOAGULANTS AND TREATMENT OF AUTOIMMUNE DISEASE | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-05-28 | — | — | US | disclosed |