SCHEMBL765763

SCHEMBL765763

O=C1CC(C(F)(F)F)=NN1c1cccc(I)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOX P28300 1/20 0.49
KMT2A Q03164 6/20 0.43
MAPT P10636 6/20 0.43
GAA P10253 4/20 0.43
KDM4E B2RXH2 3/20 0.43
APP P05067 2/20 0.41
FAAH O00519 1/20 0.41
MGLL Q99685 1/20 0.41
MEN1 O00255 5/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
ALDH1A1 P00352 3/20 0.39
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA9 Q16790 1/20 0.39
DRD3 P35462 2/20 0.39
CYP1A2 P05177 1/20 0.39
CHRM2 P08172 1/20 0.39
CYP3A4 P08684 1/20 0.39
CHRM1 P11229 1/20 0.39
TSHR P16473 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL178802 0.84 KMT2A (0.51) LOXKMT2AMAPTGAAKDM4E
SCHEMBL761303 0.84 KMT2A (0.62) LOXKMT2AMAPTGAAKDM4E
SCHEMBL178857 0.82 LOX (0.71) LOXKMT2AMAPTGAAKDM4E
SCHEMBL5463910 0.80 KMT2A (0.66) LOXKMT2AMAPTGAAKDM4E
SCHEMBL5470613 0.76 GAA (0.48) LOXKMT2AMAPTGAAKDM4E
SCHEMBL8610311 0.75 MAPT (0.51) LOXKMT2AMAPTGAAKDM4E
SCHEMBL5470298 0.74 LOX (0.44) LOXKMT2AMAPTGAAKDM4E
SCHEMBL8760115 0.70 POLB (0.54) LOXKMT2AMAPTGAAKDM4E
SCHEMBL8616032 0.69 PDCD1 (0.53) LOXKMT2AMAPTGAAKDM4E
SCHEMBL4661641 0.69 MAPT (0.65) KMT2AMAPTGAAKDM4EAPP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2050745-B1 N-PYRIDYLPIPERIDINE COMPOUND, METHOD FOR PRODUCING THE SAME, AND PEST CONTROL AGENT OTSUKA AGRITECHNO CO LTD (JP) 2012-03-21 EP disclosed