Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 2/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.66 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | P4HB | P07237 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | F10 | P00742 | 1/20 | 0.50 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7656984 | 0.99 | CYP2C9 (0.64) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| SCHEMBL7657788 | 0.89 | NPC1 (0.53) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7662470 | 0.88 | NPC1 (0.52) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| SCHEMBL7661930 | 0.83 | CYP3A4 (0.69) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL7655131 | 0.82 | CYP3A4 (0.68) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| SCHEMBL7657919 | 0.82 | F3 (0.79) | F2F10PRSS1PRSS2F7 | |
| SCHEMBL7661471 | 0.80 | CYP3A4 (0.53) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| SCHEMBL7660125 | 0.79 | CYP2C9 (0.52) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| SCHEMBL7659362 | 0.78 | CYP2C9 (0.51) | CYP2C9CYP3A4ALOX12MEN1KMT2A | |
| SCHEMBL7663108 | 0.78 | F10 (0.64) | CYP2C9CYP3A4ALOX12MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | claimed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | claimed |