⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31394958 | 0.79 | — | — | |
| SCHEMBL24003245 | 0.74 | — | — | |
| SCHEMBL11785202 | 0.72 | — | — | |
| SCHEMBL24408009 | 0.70 | — | — | |
| Bromide SCHEMBL15671513 | 0.70 | — | — | |
| SCHEMBL30574160 | 0.70 | — | — | |
| SCHEMBL5305883 | 0.70 | — | — | |
| SCHEMBL18924917 | 0.70 | — | — | |
| SCHEMBL28401035 | 0.68 | — | — | |
| Bromide SCHEMBL3390866 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127499-A1 | PROTEIN TYROSINE PHOSPHATASE INHIBITORS AND METHODS OF USE THEREOF | CALICO LIFE SCIENCES LLC (US) | 2021-06-24 | — | — | WO | disclosed |
| US-8362213-B2 | Anti-FcRH5 antibodies and immunoconjugates and methods of use | GENENTECH, INC. (US) | 2013-01-29 | — | — | US | disclosed |
| US-8278293-B2 | Diazo bicyclic Smac mimetics and the uses thereof | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-02 | — | — | US | disclosed |
| US-8143212-B2 | Dalbavancin compositions for treatment of bacterial infections | VICURON PHARMACEUTICALS INC. (US) | 2012-03-27 | — | — | US | disclosed |
| EP-2431043-A1 | Cholesterol-interacting layered phyllosilicates for suppressing gastrointestinal cholesterol absorption | Amcol International Corporation (US) | 2012-03-21 | — | — | EP | disclosed |
| EP-1959955-B1 | METHOD OF TREATING ABNORMAL CELL GROWTH | PFIZER PROD INC (US) | 2010-11-17 | — | — | EP | disclosed |
| US-20100273812-A1 | DIAZO BICYCLIC SMAC MIMETICS AND THE USES THEREOF | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2010-10-28 | — | — | US | disclosed |
| US-20100129390-A1 | DKK1 AS A UNIVERSAL TUMOR VACCINE FOR IMMUNOTHERAPY OF CANCERS | BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM | 2010-05-27 | — | — | US | disclosed |
| US-20090298749-A1 | DALBAVANCIN COMPOSITIONS FOR TREATMENT OF BACTERIAL INFECTIONS | VICURON PHARMACEUTICALS INC. | 2009-12-03 | — | — | US | disclosed |
| US-20090062913-A1 | Light powered microactuator, microfluidic dispenser and retinal prosthesis | NATIONAL SCIENCE FOUNDATION | 2009-03-05 | — | — | US | disclosed |
| US-7455844-B2 | Vaccine against streptococci | MERIAL LIMITED (US) | 2008-11-25 | — | — | US | disclosed |
| US-20070191324-A1 | Methods for treatment or prophylaxis of aldosterone-mediated pathogenic effects in a subject using an epoxy-steroidal aldosterone antagonist | WILLIAMS GORDON H | 2007-08-16 | — | — | US | disclosed |
| US-20070105703-A1 | Deuteroxyle-doped silica glass, optical member and lithographic system comprising same and method of making same | CORNING INCORPORATED | 2007-05-10 | — | — | US | disclosed |