Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 3/20 | 0.52 |
| ▸ | IGF1R | P08069 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.42 |
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.38 |
| ▸ | MAPK3 | P27361 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.35 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.35 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | RAF1 | P04049 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668541 | 0.89 | ADORA1 (0.53) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL9034810 | 0.88 | ADORA1 (0.52) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL7666486 | 0.88 | ADORA1 (0.52) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL7666482 | 0.88 | ADORA1 (0.52) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL9035165 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL9035159 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL9035178 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL7667913 | 0.84 | ADORA1 (0.49) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL7670232 | 0.84 | ADORA1 (0.53) | ADORA1IGF1RMAPK1AKT1MAPK14 | |
| SCHEMBL7665031 | 0.84 | ADORA1 (0.53) | ADORA1IGF1RMAPK1AKT1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6355640-B1 | TREATMENT OF HYPERTENSION, UROGENITAL DISORDERS AND FORMED BY WITTIG REACTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-12 | — | — | US | disclosed |