Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 15/20 | 0.53 |
| ▸ | MC5R | P33032 | 12/20 | 0.53 |
| ▸ | MC3R | P41968 | 11/20 | 0.53 |
| ▸ | MC1R | Q01726 | 11/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7658043 | 1.00 | MC4R (0.53) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6200842 | 0.85 | MC4R (0.55) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6200844 | 0.84 | MC4R (0.58) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL1309435 | 0.83 | MC4R (0.59) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL1309434 | 0.83 | MC4R (0.59) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6475531 | 0.81 | MC4R (0.54) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6215075 | 0.81 | MC4R (0.51) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6477067 | 0.81 | MC4R (0.51) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6181458 | 0.80 | MC4R (0.51) | MC4RMC5RMC3RMC1RCYP3A4 | |
| SCHEMBL6162303 | 0.80 | KMT2A (0.58) | MC4RCYP3A4KMT2ACACNA1BMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6350760-B1 | OBESITY, DIABETES, SEXUAL DYSFUNCTION; | MERCK & CO., INC. | 2002-02-26 | — | — | US | disclosed |