Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 18/20 | 0.59 |
| ▸ | F2 | P00734 | 17/20 | 0.59 |
| ▸ | F10 | P00742 | 17/20 | 0.59 |
| ▸ | F3 | P13726 | 17/20 | 0.59 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.59 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.59 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.59 |
| ▸ | PLG | P00747 | 9/20 | 0.52 |
| ▸ | PLAU | P00749 | 2/20 | 0.51 |
| ▸ | F9 | P00740 | 1/20 | 0.51 |
| ▸ | F11 | P03951 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7655067 | 0.94 | F7 (0.60) | F7F2F10F3PRSS1 | |
| SCHEMBL7660544 | 0.92 | F7 (0.57) | F7F2F10F3PRSS1 | |
| SCHEMBL7652025 | 0.91 | F7 (0.56) | F7F2F10F3PRSS1 | |
| SCHEMBL7665856 | 0.89 | F7 (0.62) | F7F2F10F3PRSS1 | |
| SCHEMBL7657789 | 0.89 | F7 (0.58) | F7F2F10F3PRSS1 | |
| SCHEMBL7660826 | 0.89 | F2 (0.59) | F7F2F10F3PRSS1 | |
| SCHEMBL7657027 | 0.88 | F7 (0.61) | F7F2F10F3PRSS1 | |
| SCHEMBL7843743 | 0.88 | F7 (0.74) | F7F2F10F3PRSS1 | |
| SCHEMBL7662116 | 0.88 | F3 (0.61) | F7F2F10F3PRSS1 | |
| SCHEMBL7664345 | 0.87 | F2 (0.59) | F7F2F10F3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |