Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 10/20 | 0.45 |
| ▸ | CTRB1 | P17538 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498222 | 0.92 | ELANE (0.44) | ELANECTRB1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6804366 | 0.91 | ELANE (0.45) | ELANECTRB1 | |
| SCHEMBL6802037 | 0.89 | ELANE (0.46) | ELANECTRB1ALDH1A1HTTNPSR1 | |
| SCHEMBL7841675 | 0.86 | ELANE (0.48) | ELANECTRB1 | |
| SCHEMBL6802038 | 0.86 | ELANE (0.48) | ELANECTRB1 | |
| SCHEMBL6806821 | 0.86 | ELANE (0.47) | ELANECTRB1 | |
| SCHEMBL6802565 | 0.86 | ELANE (0.46) | ELANECTRB1 | |
| SCHEMBL6803263 | 0.83 | ELANE (0.45) | ELANECTRB1 | |
| SCHEMBL6805565 | 0.83 | ELANE (0.43) | ELANECTRB1 | |
| SCHEMBL6505790 | 0.82 | ELANE (0.44) | ELANECTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6380189-B1 | FOR TREATING HERPES-RELATED DISORDERS | G.D. SEARLE & CO. | 2002-04-30 | — | — | US | disclosed |