Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MC5R | P33032 | 1/20 | 0.32 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | CLPP | Q16740 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7657546 | 0.88 | HRH3 (0.69) | HRH3DPP4MAPK1 | |
| SCHEMBL7652819 | 0.88 | HRH3 (0.77) | HRH3MAPK1 | |
| SCHEMBL7665250 | 0.88 | HRH3 (0.71) | HRH3CLPP | |
| SCHEMBL7655864 | 0.86 | HRH3 (0.72) | HRH3L3MBTL1MAPK1RAB9A | |
| SCHEMBL7663692 | 0.85 | HRH3 (0.67) | HRH3MAPK1RAB9A | |
| SCHEMBL7659427 | 0.85 | HRH3 (0.67) | HRH3RAB9A | |
| SCHEMBL7654578 | 0.84 | HRH3 (0.65) | HRH3L3MBTL1MAPK1RAB9A | |
| SCHEMBL7663686 | 0.84 | HRH3 (0.65) | HRH3MAPK1RAB9A | |
| SCHEMBL7655188 | 0.82 | HRH3 (0.42) | HRH3 | |
| SCHEMBL7660585 | 0.81 | HRH3 (0.62) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002085861-A1 | IMIDAZOLIDINE COMPOUNDS AND THEIR USE AS CXCR3 ANTAGONISTS | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-10-31 | — | — | WO | disclosed |
| US-6469002-B1 | COMPOUNDS WHICH MODULATE CHEMOKINE RECEPTOR ACTIVITY AND ARE USEFUL IN TREATMENT OF INFLAMMATORY DISEASES | MILLENNIUM PHARMACEUTICALS, INC. | 2002-10-22 | — | — | US | disclosed |