Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 15/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | CTRC | Q99895 | 2/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7662157 | 0.89 | CMA1 (0.40) | CMA1KMT2AMEN1ATMELANE | |
| SCHEMBL7658536 | 0.89 | CMA1 (0.52) | CMA1KMT2AMEN1ATMCTRC | |
| SCHEMBL7655928 | 0.86 | TACR1 (0.43) | ELANE | |
| SCHEMBL7669800 | 0.86 | TACR1 (0.39) | CMA1ELANE | |
| SCHEMBL5711243 | 0.85 | CMA1 (0.50) | CMA1KMT2AMEN1ATMCTRC | |
| SCHEMBL7655683 | 0.81 | CMA1 (0.43) | CMA1ACEELANE | |
| SCHEMBL7661080 | 0.80 | CCR1 (0.46) | CMA1ELANE | |
| SCHEMBL7662744 | 0.80 | KMT2A (0.43) | CMA1KMT2ACTRC | |
| SCHEMBL7661700 | 0.80 | CMA1 (0.58) | CMA1KMT2AMEN1ATMCTRC | |
| SCHEMBL7663110 | 0.79 | CAPN1 (0.39) | CMA1ELANE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6410576-B1 | ANTIINFLAMMATORY AGENTS; CARDIOVASCULAR DISORDERS | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 2002-06-25 | — | — | US | disclosed |