SCHEMBL7658647

SCHEMBL7658647

CC1(c2cccc3ccccc23)C(=O)N(CCCn2ccnc2)C(=O)N1Cc1ccccc1CN

nearest known ligand 0.84

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
FNTA P49354 20/20 0.84
FNTB P49356 20/20 0.84

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7662335 0.91 FNTA (1.00) FNTAFNTB
SCHEMBL7651908 0.88 FNTA (0.88) FNTAFNTB
SCHEMBL7659605 0.88 FNTA (1.00) FNTAFNTB
SCHEMBL7656162 0.87 FNTA (1.00) FNTAFNTB
SCHEMBL7660503 0.86 FNTA (0.75) FNTAFNTB
SCHEMBL7653387 0.85 FNTA (1.00) FNTAFNTB
SCHEMBL7658427 0.85 FNTA (0.79) FNTAFNTB
SCHEMBL7655196 0.83 FNTA (1.00) FNTAFNTB
SCHEMBL7659442 0.83 FNTA (1.00) FNTAFNTB
SCHEMBL7655854 0.83 FNTA (1.00) FNTAFNTB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6384061-B1 HYDANTOIN COMPOUNDS REPRESENTED BY FORMULA (I) WHICH SHOWS AN INHIBITORY ACTIVITY AGAINST FARNESYL TRANSFERASE, AND THUS CAN BE USED AS AN ANTI-CANCER AGENT, OR PHARMACEUTICALLY ACCEPTABLE SALTS LG CHEMICAL LTD. (KR) 2002-05-07 US disclosed
EP-1000036-A1 HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE LG CHEMICAL LIMITED (KR) 2000-05-17 EP disclosed
WO-1999005117-A1 HYDANTOIN DERIVATIVES HAVING AN INHIBITORY ACTIVITY FOR FARNESYL TRANSFERASE LG CHEMICAL LTD. (KR) 1999-02-04 WO disclosed