SCHEMBL765904

SCHEMBL765904

COC(=O)CCC[C@@H](C)CCCN1C(=O)CCC[C@@H]1/C=C/C(O)Cc1ccccc1

nearest known ligand 0.67

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 16/20 0.67
PTGER2 P43116 2/20 0.59
PTGER3 P43115 2/20 0.59

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4377080 0.91 PTGER4 (0.73) PTGER4PTGER2PTGER3
SCHEMBL4375236 0.91 PTGER4 (0.73) PTGER4PTGER2PTGER3
SCHEMBL4377077 0.91 PTGER4 (0.73) PTGER4PTGER2PTGER3
SCHEMBL4375231 0.91 PTGER4 (0.73) PTGER4PTGER2PTGER3
SCHEMBL4377084 0.91 PTGER4 (0.73) PTGER4PTGER2PTGER3
SCHEMBL5245575 0.90 PTGER4 (0.71) PTGER4PTGER2PTGER3
SCHEMBL5245568 0.90 PTGER4 (0.71) PTGER4PTGER2PTGER3
SCHEMBL14301481 0.89 PTGER4 (0.73) PTGER4PTGER2PTGER3
SCHEMBL14277472 0.89 PTGER4 (0.72) PTGER4PTGER2PTGER3
SCHEMBL758004 0.87 PTGER4 (0.73) PTGER4PTGER2PTGER3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1761495-B1 PIPERIDINYL PROSTAGLANDIN ANALOGS AS OCULAR HYPOTENSIVE AGENTS ALLERGAN INC (US) 2012-03-21 EP disclosed