Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 19/20 | 0.72 |
| ▸ | PDGFRA | P16234 | 19/20 | 0.72 |
| ▸ | ACHE | P22303 | 1/20 | 0.61 |
| ▸ | BACE1 | P56817 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7659180 | 1.00 | PDGFRB (0.72) | PDGFRBPDGFRAACHEBACE1 | |
| SCHEMBL7663136 | 0.92 | PDGFRB (0.72) | PDGFRBPDGFRAACHEBACE1 | |
| SCHEMBL7657597 | 0.92 | PDGFRB (0.72) | PDGFRBPDGFRA | |
| SCHEMBL7663152 | 0.92 | PDGFRB (0.72) | PDGFRBPDGFRAACHEBACE1 | |
| SCHEMBL7657593 | 0.92 | PDGFRB (0.72) | PDGFRBPDGFRA | |
| SCHEMBL7658361 | 0.92 | PDGFRB (0.73) | PDGFRBPDGFRA | |
| SCHEMBL7658358 | 0.92 | PDGFRB (0.73) | PDGFRBPDGFRA | |
| SCHEMBL7655714 | 0.92 | PDGFRB (0.75) | PDGFRBPDGFRA | |
| SCHEMBL7655717 | 0.92 | PDGFRB (0.75) | PDGFRBPDGFRA | |
| SCHEMBL7661435 | 0.92 | PDGFRB (0.72) | PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6423716-B1 | Nitrogenous heterocyclic compounds | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2002-07-23 | — | — | US | disclosed |
| EP-1067123-A1 | NITROGENOUS HETEROCYCLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 2001-01-10 | — | — | EP | disclosed |