Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F7 | P08709 | 20/20 | 0.71 |
| ▸ | F9 | P00740 | 9/20 | 0.71 |
| ▸ | F10 | P00742 | 7/20 | 0.71 |
| ▸ | F11 | P03951 | 5/20 | 0.71 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.71 |
| ▸ | PRSS2 | P07478 | 5/20 | 0.71 |
| ▸ | PRSS3 | P35030 | 5/20 | 0.71 |
| ▸ | F2 | P00734 | 5/20 | 0.71 |
| ▸ | PLAU | P00749 | 3/20 | 0.71 |
| ▸ | F3 | P13726 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7660157 | 0.94 | F7 (0.80) | F7F9F10F11PRSS1 | |
| SCHEMBL7659217 | 0.92 | F7 (0.82) | F7F9F10F11PRSS1 | |
| SCHEMBL7658098 | 0.91 | F7 (0.70) | F7F9F10F11PRSS1 | |
| SCHEMBL7651355 | 0.91 | F7 (0.70) | F7F9F10F11PRSS1 | |
| SCHEMBL7658253 | 0.90 | F7 (0.69) | F7F9F10F11PRSS1 | |
| SCHEMBL7657424 | 0.90 | F7 (0.87) | F7F9F10F11PRSS1 | |
| SCHEMBL7855056 | 0.89 | F7 (0.64) | F7F9F10F11PRSS1 | |
| SCHEMBL7665721 | 0.88 | F7 (0.67) | F7F9F10F11PRSS1 | |
| SCHEMBL7659073 | 0.87 | F7 (0.64) | F7F9F10F11PRSS1 | |
| SCHEMBL7661546 | 0.86 | F7 (0.64) | F7F9F10F11PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6358960-B1 | FOR THERAPY OF INTRAVASCULAR COAGULATION, CORONARY THROMBOSIS, CEREBRAL INFARCTION, CEREBRAL EMBOLISM, TRANSIENT ISCHEMIC ATTACK, CEREBROVASCULAR DISORDERS, PULMONARY VASCULAR DISEASES, DEEP VENOUS THROMBOSIS, ETC. | ONO PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |
| EP-1078917-A1 | AMIDINO DERIVATIVES AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | ONO PHARMACEUTICAL CO., LTD. (JP) | 2001-02-28 | — | — | EP | disclosed |