Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 17/20 | 0.55 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.45 |
| ▸ | PTPRC | P08575 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7595420 | 0.90 | PTPN1 (0.45) | PTPN1PTPN2PTPRC | |
| SCHEMBL7599756 | 0.86 | PTPN1 (0.39) | PTPN1PTPN2 | |
| SCHEMBL7189550 | 0.86 | PTPN1 (0.47) | PTPN1PTPN2PTPRC | |
| SCHEMBL7193736 | 0.85 | PTPN1 (0.38) | PTPN1 | |
| SCHEMBL7183011 | 0.85 | PTPN1 (0.38) | PTPN1 | |
| SCHEMBL7593008 | 0.85 | PTPN1 (0.39) | PTPN1 | |
| SCHEMBL7659253 | 0.85 | PTPN1 (0.70) | PTPN1PTPN2PTPRC | |
| SCHEMBL7594345 | 0.84 | PTPN1 (0.44) | PTPN1PTPN2 | |
| SCHEMBL7189856 | 0.84 | PTPN1 (0.39) | PTPN1PTPN2 | |
| SCHEMBL7595556 | 0.84 | TP53 (0.37) | PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6498151-B2 | PROTEIN TYROSINE PHOSPHATASES INHIBITORS, ESPECIALLY AS ANTIDIABETIC AGENTS | MERCK FROSST CANADA & CO. (CA) | 2002-12-24 | — | — | US | claimed |