Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADA | P00813 | 8/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7668675 | 0.85 | ADA (0.51) | ADATAAR1 | |
| SCHEMBL7661719 | 0.85 | ADA (0.54) | ADA | |
| SCHEMBL7670511 | 0.84 | ADA (0.50) | ADANR3C2 | |
| SCHEMBL7659436 | 0.83 | ADA (0.71) | ADANR3C2 | |
| SCHEMBL7659109 | 0.83 | ADA (0.66) | ADA | |
| SCHEMBL7452599 | 0.80 | CYP4F2 (0.52) | ADA | |
| SCHEMBL6172982 | 0.80 | ADA (0.47) | ADANR3C2MAOBEPHX1 | |
| SCHEMBL7656871 | 0.80 | ADA (0.46) | ADA | |
| SCHEMBL6173090 | 0.77 | ADA (0.51) | ADA | |
| SCHEMBL7664221 | 0.73 | ADA (0.70) | ADA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6359145-B1 | ADENOSINE DEAMINASE INHIBITOR; ANTIINFLAMMATORY AGENTS; IMMUNOSUPPRESSANT | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-03-19 | — | — | US | disclosed |