Sugi Predict

Sugi Predict / Compounds / SCHEMBL7659449

SCHEMBL7659449

SCHEMBL7659449

CC(=O)N[C@@H](Cc1ccc(OP(=O)(O)O)cc1)C(=O)N[C@@H]1CCCCc2cc(OCC3CCCCC3)c(C(N)=O)cc21

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
▸ SRC P12931 19/20 1.00
▸ YES1 P07947 2/20 0.69
▸ LCK P06239 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7652529 0.93 SRC (0.87) SRCYES1LCK
SCHEMBL7658107 0.93 SRC (0.87) SRCYES1LCK
SCHEMBL7654913 0.90 SRC (0.82) SRCYES1LCK
SCHEMBL7653006 0.90 SRC (0.82) SRCYES1LCK
SCHEMBL7653010 0.90 SRC (0.82) SRCYES1LCK
SCHEMBL7653013 0.90 SRC (0.82) SRCYES1LCK
SCHEMBL29432639 0.89 SRC (1.00) SRCYES1LCK
SCHEMBL7245569 0.89 SRC (1.00) SRCYES1LCK
SCHEMBL31061705 0.89 SRC (1.00) SRCYES1LCK
SCHEMBL4997480 0.89 SRC (1.00) SRCYES1LCK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6482852-B2 UE TREATING PROLIFERATIVE DISEASE, CANCER, RESTENOSIS, OSTEOPOROSIS, INFLAMMATION, ALLERGIES, OR CARDIOVASCULAR DISEASE; INHIBITION OF SH2-MEDIATED SIGNALING ARIAD PHARMACEUTICALS, INC. 2002-11-19 — — US disclosed